Prof. Dr. Stefan Kalkhof's research interests include the search for biomarkers and the development of diagnostic assays, the toxicological evaluation of chemicals – both with regard to humans and bacteria – and the investigation of wound-healing stimulating implant materials. Using mass spectrometry, it is possible to develop methods that allow proteins and their ligands such as toxins and active substances to be extensively characterized and quantified. Prof. Kalkhof enriches the research focus "Smart Sensing, Automation and Analytics" at Coburg University of Applied Sciences with his expertise in the field of instrumental bioanalytics (GC-MS, LC-MS, AAS, ICP-MS, IR, GPC) as well as in the development of molecular analytical methods. Through his secondary position as head of the "Protein Biomarkers" working group in the "Therapy Validation" department of the Fraunhofer Institute for Cell Therapy and Immunology, he has a direct interface that allows GLP-compliant studies to be carried out (clean room, quality assurance and other large-scale equipment).

• Bioanalytics
• Mass spectrometry
• Protein analysis/proteomics
• Molecular toxicology
• Structural biology

Within the university

• Program Director Master Bioanalytics
• Student Advisory Service Master Bioanalytics
• Head of the Institute for Bioanalytics
• Laboratory Management Faculty of Applied Natural Sciences and Health – Chemistry Center
• Member of the Analytics4Health Doctoral Center
• Head of the One Health research group

Outside the university

Head of the Protein Biomarkers working group
"Therapy Validation" department
Fraunhofer Institute for Cell Therapy and Immunology

• Since 2016: Research professorship at the Coburg University of Applied Sciences
• since 2015: Professor of Instrumental Bioanalytics at the Coburg University of Applied Sciences
• since 2012: Habilitation candidate and guest lecturer in the Department of Analytical Chemistry at the University of Leipzig
• 2008 – 2016: Head of the "Mass Spectrometry" working group, Department of Proteomics (Head Prof. Martin von Bergen), Helmholtz Centre for Environmental Research – UFZ
• 2004 – 2008: University of Leipzig, Analytical Chemistry / University of Halle, Pharmacy(working group Prof. Andrea Sinz), PhD (Dr. rer. nat.): "Investigation of laminin self-interaction using chemical cross-linking, mass spectrometry and computational modeling" awarded by BAYER-Bitterfeld AG
  Summary Diss. (2.4 MB)
• 2006: Vanderbilt University, Center for Structural Biology, Nashville, USA (working group Prof. Jens Meiler), research stay: Tertiary structure prediction of proteins and protein complexes, Meiler Lab
• 2003 – 2004: University of Leipzig, Diploma: "Structural investigation of a calmodulin / sk-MLCK peptide complex"
• 2002: University of Antwerp (UIA), research stay: "Investigation of polymers using secondary ion mass spectrometry"
• 1999 – 2004: University of Leipzig, degree course in chemistry